After the recent update of WordPress 2.8 I have become aware that my site had an unreasonably long load time. In my search for the answer to my problem I look through various wordpress optimizing blogs, who recommended more or less the same

• De-activate unused plugins
• Reduce the number of HTTP requests
• Use WP-Cache
• Enable GZip with WP-Cache

I found a bunch of plugins that I did not really need, which reduced my load time a great deal. However, I found that I no longer had access to WP-cache and WP-Tweaks, which I had previously enabled. So I removed them from my server, and suddenly I went from a responds time 36 sec to below 10 sec! I Do not know if others experience the same kind of problems, but I thought I would be worth sharing.